016) and between the ball and chair conditions (p = 0.015), respectively. Similarly, there were significant differences in the left foot COP speed in the AP direction between the ball and air-cushion conditions (p = 0.019) and between the ball and chair conditions (p = 0.028), respectively. The purpose of this study was to determine if active sitting would result in increased trunk motion and alterations of foot COP. Three sitting surfaces were introduced in this study: stability ball, air-cushion, and a hard surface (chair). Subjects performed a 30-min sitting on each of the sitting surfaces. Trunk motion and foot COP data were

collected and analyzed. Our findings indicate that the average T_COM and T_AVEL significantly increased with increased NVP-AUY922 order seating surface compliance. In addition, there were differences in the average speeds of the right and left foot COP in the AP direction between the ball and air cushion conditions and the ball and chair conditions.

We had hypothesized Roxadustat cell line that average T_COMs and T_AVELs would be influenced by sitting compliance. This hypothesis was supported. We found there were greater average T_COMs in the AP and longitudinal directions of spinal motion as surface compliance increased. There was also increased T_AVEL associated with the ball condition around the AP and longitudinal axes. This finding is in agreement with previous research,6 which reported that sitting on unstable surfaces induces greater spinal motion. It was reported that hypomobility of spine TCL due to a lack of mechanical stimulus yields adaptive changes that are related to reduced nutrient transport.5 There is a strong correlation between reduced or disrupted disc nutrition and occurrence of disc degeneration.14 Thus, increasing T_COM through active sitting may help prevent spinal hypomodiblity

and improve spine health. It is worth noting that the air-cushion condition resulted in greater trunk motion in the ML direction than the chair condition. It is possible that the subtle trunk motion in the ML direction during active sitting using an air-cushion could introduce dynamic mechanic-stimulus to lateral aspects of vertebrates. The potential risk of prolonged asymmetric intervertebral disc compression could be offset and the risk of disc herniation could be lowered. We had hypothesized that sitting on a stability ball or an air-cushion would increase trunk T_ANG range of motion. This hypothesis was not supported. There were no significant differences in T_ANG among the three sitting conditions. As the subjects were required to focus on a TV screen during the testing, it was essential to maintain a stable upper body during sitting so that the video viewing task would not be interfered. In this study, subjects were able to maintain an upright trunk position without experiencing increased range of motion when sitting on unstable surfaces.