4%) in the generator exchange group could not be defibrillated using the standard approach. All of those patients had either chronic amiodarone therapy, secondary prevention or a cardiac resynchronization therapy device (CRT). GSI-IX research buy In univariate analysis, amiodarone therapy, dilated cardiomyopathy, and lower ejection fraction were predictors of failure. Conclusion: Our

study’s results as well as a review of the current literature favor shock testing, especially in patients with specific risk factors as mentioned above. (J Cardiovasc Electrophysiol, Vol. 24, pp. 437-441, April 2013)”
“Aims The study was designed to test the influence of the temporal resolution, at which tissue Doppler imaging (TDI) and speckle tracking imaging PP2 solubility dmso (STI) operate, on the accurate assessment of left ventricular (LV) untwist rate (UR).\n\nMethods and results Echo imaging and invasive LV pressure measurements

were performed during right atrial (RA) pacing and dobutamine challenge in eight pigs. LV torsion and torsional rate profiles were analysed from grey scale and tissue Doppler data ( apical and basal short axis) at frame rates of 82 +/- 17 and 183 +/- 14 Hz, respectively. Temporal subsampling of TDI data sets was performed at 82 +/- 6 Hz in order to mimic the mean temporal resolution of STI and the LV torsional curves were again extracted. At rest, LV UR values were comparable for both imaging techniques. However, during dobutamine stimulation, TDI estimated peak UR was predominantly higher than UR measured by STI (-112.1 +/- 64.58 degrees/s vs. -75.5 +/- 31.48 BTSA1 clinical trial degrees/s, P < 0.05). The similarity of LV UR measurements with respect to the STI/TDI data was examined by a Bland-Altman analysis.\n\nConclusion Although both methods regarding LV UR correlated well, these methods cannot be interchanged. STI showed a bias

to underestimate UR at high values.”
“Real-time 4D full-range complex-conjugate-free Fourier-domain optical coherence tomography (FD-OCT) is implemented using a dual graphics processing units (dual-GPUs) architecture. One GPU is dedicated to the FD-OCT data processing while the second one is used for the volume rendering and display. GPU accelerated non-uniform fast Fourier transform (NUFFT) is also implemented to suppress the side lobes of the point spread function to improve the image quality. Using a 128,000 A-scan/second OCT spectrometer, we obtained 5 volumes/second real-time full-range 3D OCT imaging. A complete micro-manipulation of a phantom using a microsurgical tool is monitored by multiple volume renderings of the same 3D date set with different view angles. Compared to the conventional surgical microscope, this technology would provide the surgeons a more comprehensive spatial view of the microsurgical site and could serve as an effective intraoperative guidance tool.