At the 11th day, both captopril-treated groups had more NOx in wound fluid compared to DM-control group. VEGF concentration was significantly higher in both captopril-treated groups
versus DM-control group (P < .05). There were significant higher wound healing scores in captopril-treated groups compared with DM-control group (P < .05). These results suggest that captoprilmight be useful in diabetic wound healing.”
“AimChromosomal abnormalities are an important cause of repeated miscarriage. Several studies have discussed the association between chromosomal abnormalities and repeated miscarriage. This study attempts to describe the pattern of miscarriage in this group of women and the eventual pregnancy outcome of couples with chromosomal abnormalities compared with couples with unexplained repeated pregnancy loss.
Material Thiazovivin clinical trial and MethodsThis was a retrospective study involving 795 couples with repeated miscarriages.
of 795 couples, 28 (3.52%) were found to have a chromosomal abnormality (carrier group). Over half (65.5%) of the chromosomal abnormalities were balanced reciprocal translocations. After referral, this carrier group had a total of 159 pregnancies, leading to 36 live births (22.6%) among 18 couples. The after referral miscarriage rate EGFR signaling pathway in the chromosomal anomaly group (55.6%) was significantly (P<0.01) higher than that in the unexplained recurrent miscarriage group (28.1%). In couples with chromosomal HDAC inhibitor anomaly, the miscarriages were more likely to occur between 6 and 12 weeks’ gestation.
ConclusionsThe encouraging cumulative live birth rate of 64.3% for couples with chromosomal anomaly and repeated miscarriage suggests that further attempts at natural conception are a viable option.”
“In this article our aim was to evaluate mass cultivation of S. marianum hairy roots in a bioreactor to produce silymarin. The effects of methyl jasmonate (MJ) elicitation on the accumulation of silymarin and the extent of the MJ-induced oxidative damage were investigated in bioreactor
hairy root cultures of S. marianum. The growth rate of the bioreactor hairy root cultures was higher than that of those in a shake flask after 3 weeks. Silymarin accumulation was increased from 0.13 mg g(-1) DW in non-treated hairy roots to 0.22mg g(-1) DW in hairy roots 72 h after 100 mMMJ treatment. Guaiacol peroxidase and ascorbate peroxidase were activated by MJ 72 h after treatment, being 3.2- and 1.3-fold higher, respectively, than that of the control. An increase in enzymatic activity suggests increased scavenging of reactive oxygen species, indicating the tolerance to MJ stress. These results suggest that MJ elicitation is beneficial for silymarin production using bioreactor hairy root cultures.