Furthermore, fluorescent BSB-Me nanocrystals could be used in biological applications such as fluorescent bioimaging of cells and tissue similar to that in our previous work. Authors’ information KB is an Endowed Chair Associate Professor at the Department of Visual Regenerative Medicine, selleck inhibitor Osaka University Graduate School of Medicine, Japan, and KN is a Professor and a medical doctor at the Department of Ophthalmology, Osaka University Graduate

School of Medicine, Japan. Acknowledgements This study was partially supported by a Challenging Exploratory Research (no. 25560223) and Grant-in-Aid for Young Scientists (A) (no. 24680054) from the Japan Society for the Promotion of Science. We thank Dr. Yasunobu Wada for his technical support to the experiments. References 1. Yang J, Fang HH, Ding R, Lu SY, Zhang YL, Chen QD, Sun HB: High-quality large-size organic crystals prepared by improved physical vapor growth technique and their optical gain properties. J Phy Chem C 2011, 115:9171–9175.CrossRef 2. Liu SH, Wang WCM, Briseno AL, Mannsfeld SCE, Bao ZN: Controlled deposition of crystalline organic semiconductors for field-effect-transistor applications. Adv Mater 2009, 21:1217–1232.CrossRef 3. Nakanotani H, Saito M, Nakamura H, Adachi C: Emission color tuning in ambipolar organic single-crystal field-effect transistors by dye-doping. Adv Funct Mater 2010,

Selleckchem 3-MA 20:1610–1615.CrossRef 4. Sasaki F, Kobayashi S, Haraichi S, Fujiwara S, Bando K, Masumoto Y, Hotta S: Microdisk and microring lasers of thiophene-phenylene co-oligomers embedded in Si/SiO 2 substrates. Adv Mater 2007, 19:3653–3655.CrossRef 5. Fang HH, Yang J, Ding R, Chen QD, Wang L, Xia H, Feng J, Ma YG, Sun HB: Polarization dependent two-photon properties in an organic crystal. Appl Phys Lett 2010, 97:101101.CrossRef 6. Kabe R, Nakanotani H, Sakanoue T, Yahiro M, Adachi C: Effect of molecular morphology on amplified spontaneous emission of bis-styrylbenzene derivatives. Adv Mater 2009, 21:4034–4038.CrossRef 7. Nakanotani H, Adachi C: Organic light-emitting diodes containing multilayers of organic single

crystals. Appl Phys Lett 2010, 96:053301.CrossRef 8. Baba K, Kasai H, Nishida K, Nakanishi H: Poly( N -isopropylacrylamide)-based thermoresponsive behavior of fluorescent Tolmetin organic nanocrystals. Jpn J Appl Phys 2011, 50:010202. 9. Baba K, Nishida K: Calpain inhibitor nanocrystals prepared using Nano Spray Dryer B-90. Nanoscale Res Lett 2012, 7:436.CrossRef 10. Baba K, Nishida K: Steroid nanocrystals prepared using the Nano Spray Dryer B-90. Pharmaceutics 2013, 5:107–114.CrossRef 11. Baba K, Kasai H, Okada S, Oikawa H, Nakanishi H: Novel fabrication process of organic microcrystals using microwave-irradiation. Jpn J Appl Phys 2000, 39:L1256-L1258.CrossRef 12. Katagi H, Kasai H, Okada S, Oikawa H, Komatsu K, Matsuda H, Liu ZF, Nakanishi H: Size control of polydiacetylene microcrystals.