Spindle cells were bland and monomorphic, with minimal cellular variation. There was no anaplasia or specific mesenchymal differentiation.

Immunohistochemical stains on the cell block were positive for vimentin and bcl-2. A diagnosis of spindle cell neoplasm was rendered, it was believed to be a second neoplasm unrelated to the colonic adenocarcinoma. The main diagnostic consideration was synovial sarcoma. On resection, the neoplasm demonstrated t(x: 18) chromosomal translocation Napabucasin by fluorescence in situ hybridization.

Conclusion

In a spindled cell neoplasm arising as a single peripheral pulmonary nodule, monophasic spindle synovial sarcoma should be considered in the differential diagnosis; detection of the t(x;18) chromosomal translocation call confirm the diagnosis.

(Acta Cytol 2009;53:105-108)”
“Switchable voltage modulation of the magnetic properties is reported in different multiferroic bilayers with magnetic films grown on pre-poled ferroelectric substrates, based on the magnetooptical Kerr effect observations. The dynamic voltage control of the magnetic coercive field (H-c) is dependent not only on the materials properties of each ferroic layer, but also on the bias voltage history. The H-c versus electric field behaviors essentially track the dependence of the piezostrains of the substrates on the bias voltage. ARS-1620 solubility dmso The observations demonstrate that H-c in such multiferroic bilayers can be controlled by voltage via strain-mediated magnetoelectric coupling and that the H-c change is not an artifact due to a heating effect. (C) 2011 American Institute of Physics. [doi:10.1063/1.3626748]“
“Spontaneous tubal twin pregnancy is a rare condition with an incidence of 1 in every 125,000 pregnancies. We present the

case of a unilateral tubal twin ectopic pregnancy treated with single-dose methotrexate.

A 26-year-old https://www.selleck.cn/TGF-beta.html nulliparous woman was admitted to our clinic with a complaint of vaginal bleeding and leftside pelvic pain. Her serum beta-human chorionic gonadotropin (beta-hCG) level was 18,780 mIU/mL and ultrasound revealed tubal twin pregnancy of 7 weeks’ gestation. Because her vital signs were stable and no sign of tubal rupture was present, we performed single-dose (100 mg) methotrexate intramuscularly. In the follow-up, serum beta-hCG levels were found to be 7,600 mIU/ml on day 7, 948 mIU/ml on day 20, 126 mIU/ml on day 26 and < 10 mIU/ml on day 42.

Methotrexate theraphy may be preferred in tubal twin ectopic pregnancies when the vital signs of the patient are stable and the fetal cardiac activities are negative.