The area of research combining molecular Biotechnology and Agriculture is called Molecular farming or pharming. The proteins produced in transgenic plants for therapeutic use, are of three types – (i) antibodies, (b) proteins and (iii) vaccines. Antibodies directed against dental caries, rheumatoid arthritis, cholera, E. click here coli diarrhea, malaria, certain cancers, HIV, rhinovirus,
influenza, hepatitis B virus and herpes simplex virus are known to be produced in transgenic plants. Vaccines against infectious diseases of the gastro intestinal tract have been produced in plants like potato and bananas. 18 The another appropriate target would be cereal grains. An anti cancer antibody has recently expressed in rice and wheat seed that recognizes cells of lung, breast and colon cancer and hence could be useful in both diagnosis and therapy in the future. Selleckchem Kinase Inhibitor Library 19 Important advantage of GM food is its enhanced ability to withstand long-distance transportation. The GM crops are picked, when still green are allowed to ripen during transportation, therefore yielding a longer shelf life. Even with prolonged shipping and storing periods, the product reaches its destination without spoiling. According to the manufacturers of these GM crops, using these seeds will yield a number of benefits, including increased yields and decreased costs. They push GM crops as a second “Green
Revolution” in a World, with billions of hungry mouths to feed. The use of transgenic crops was an issue for many years. Many concerns have been raised and these are falling into two categories. 1. A concern, about what affect genetically Endonuclease modified material, could have on human health. For example, transgenic crops have been suggested to cause allergies in some people, although
it is uncertain, whether transgenic crops are the source of this reaction.20 Furthermore, the antibiotic resistance genes, placed in these crops have been suggested to cause resistance to antibiotics, leading to super bugs, which cannot be killed with antibiotic treatments.21 The population being uncomfortable with ingesting DNA that originated from another source, like virus or bacteria. The following are, however, potential issues of concern for plant protein production. 1. Allergic reactions to plant protein glycans and other plant antigens. In the United States the Coordinated framework for Regulation of Biotechnology governs the regulation of transgenic organisms, including plants. The Government’s view, which we share, is that, this is impractical and that the methods recommended by the World Health Organization are adequate to ensure that any possibility of an adverse effect on human health from a GM food can be detected. The three Agencies involved in this are: ➢ USDA Animal and Plant Health Inspection Service who state that the Biotechnology Regulatory Services (BRS) program of the U.S.