The proposed framework was called the dual competition model to reflect the suggestion that PFT�� cell line affective significance influences competition at both the perceptual and executive levels (Figure 2) – and because the impact is due to both emotion and motivation, although the latter is not discussed here (but see ref 90). Figure 2. Cognitive-emotional interactions. Affective value interacts with both perceptual and executive processes. Objects compete for limited Inhibitors,research,lifescience,medical perceptual processing capacity and control of behavior.91,92 Because processing capacity is limited, selective
attention to one part of the visual field comes at the cost of neglecting other parts. Thus, a popular notion is that there is competition for neural resources.91,93 As described below, to understand the flow of information processing more generally, it is necessary to go beyond the role of perceptual competition, and explicitly incorporate the impact of executive control functions on processing. Behavioral research Inhibitors,research,lifescience,medical supports the notion that executive control is not unitary and that different mechanisms
may have their own limited processing capacities, or resources.94,95 Neuropsychological research also supports the dissociation of cognitive functions, consistent with the “fractionation” of the central executive.96,97 Yet, ample Inhibitors,research,lifescience,medical evidence suggests some unity of executive functions, specifically that Inhibitors,research,lifescience,medical certain mechanisms are shared across them.98,99 This capacity-sharing has important implications for the understanding of human information processing because it leads to executive competition: subcomponents of
executive control are mutually interacting, such that resources devoted to one component will not be available to other functions. Perceptual competition Perceptual competition, which takes place in visual cortex, is affected by emotional content. As discussed, the amygdala is well positioned to implement the enhancement of visual activity given that its efferents reach multiple levels of the visual cortex, including primary visual cortex.23 Although Inhibitors,research,lifescience,medical the role of the amygdala in the modulation of visual processing is often emphasized in the literature, several other mechanisms likely play important roles, too.100 A second modulatory source may involve the orbitofrontal cortex20 (Figure 3A), a structure that has important roles in the evaluation of sensory Liothyronine Sodium stimuli.101 The orbitofrontal cortex is reciprocally interconnected with visual cortex, especially the more anterior portions of the ventral stream,12,102 and is thus capable of influencing evoked responses in visual cortex based on affective value. Figure 3. Interactions between emotion and perception. (A) Visual processing is suggested to be modulated by affective value via several mechanisms, including those involving projections from the amygdala, basal forebrain, orbitofrontal cortex, and possibly hypothalamus …