The restricted resources of cells strictly limit the number of their regulatory methods; hence, cells must adopt, as compensation, special mechanisms to deal with the simultaneous occurrence of environmental changes. We hypothesize that cells

use various control logics to integrate information about independent environmental changes related to a cell task and represent the resulting effects of the different ways of integration by logical functions. Using the notion of equivalence classes in set theory, we describe the mathematical classification of the effects into biologically unequivalent ones realized by different control logics. Our purely mathematical and systematic classification PP2 chemical structure of logical functions reveals three elementary control logics with different biological relevance. To better understand their biological significance, we consider examples of biological systems that use these elementary control logics. (C) 2007 Elsevier Ltd. All rights reserved.”
“With large amounts of experimental data, modern molecular biology needs appropriate methods to deal with biological sequences. In this work, we apply a statistical method (Pearson’s chi-square test) to recognize the signals appear in the whole genome of the Escherichia coli. To show the effectiveness

of the method, we compare the Pearson’s chi-square test with linguistic complexity https://www.selleckchem.com/products/CAL-101.html on the complete genome of E coli. The results suggest that Pearson’s chi-square test is an efficient method for distinguishing genes (coding regions) form pseudogenes (noncoding regions). On the other hand, the performance of the linguistic complexity is much lower than the chi-square test method. We also use the Pearson’s chi-square test method to determine which parts of the Open Reading Frame (ORF) have significant effect on discriminating genes form pseudogenes.

Moreover, different complexity measures and Pearson’s chi-square test applied on the genes with high value of Pearson’s chi-square statistic. We also compute the measures on homologous of these genes. The results illustrate that there is a region Rocuronium bromide near the start codon with high value of chi-square statistic and low complexity that is conserve between homologous genes. (C) 2007 Elsevier Ltd. All rights reserved.”
“Background A fully bioabsorbable drug-eluting coronary stent that scaffolds the vessel wall when needed and then disappears once the acute recoil and constrictive remodelling processes have subsided has theoretical advantages. The bioasorbable everolimus-eluting stent (BVS) has a backbone of poly-L-lactic acid that provides the support and a coating of poly-D,L-lactic acid that contains and controls the release of the antiproliferative agent everolimus. We assessed the feasibility and safety of this BVS stent.