The study uses a combination of primary and secondary data to provide baseline knowledge on the concept of herbalism, endogenous knowledge of medicinal plants, pharmaceutical uses, marketing status and threats to sustainable development. It establishes an ethno-medicinal plant inventory consisting of a total of 30 plants with major ailments. In terms of life form, 70% were composed of trees, 6.6% shrubs, 10% climbers and 13.3% herbs. Some 70% of these plants are locally marketed and 66.6% have other non-medicinal uses. The paper identifies the stresses and vulnerabilities
of the plants and the scope for western biomedical practitioners to assess this traditional knowledge, that is, methods of testing, refining and validating
indigenous knowledge in traditional medicine in order to support the process of integration. It finally posits that since different paradigms of health and illness stand in the way of real integration, western this website biomedicine and African traditional medicine may remain apart as two parallel systems hence the need to locate and catalog these plants for the identification of their pharmaceutical properties.”
“Background: Men with prostate cancer will not die of the disease until it progresses to the metastatic castration-resistant stage. At that stage, find more the median survival is 9 to 30 months.
Methods: Recently approved and emerging treatments for metastatic castration-resistant prostate cancer (mCRPC) were reviewed based on their mechanisms of action, as well as sequencing and combining these treatments with existing options.
Results: Advances in androgen deprivation therapy, immunotherapy, bone-targeted therapy, and chemotherapy have led to approvals of abiraterone acetate, sipuleucel-T, denosumab, and cabazitaxel for the treatment of mCRPC. Despite
improvements in patient survival and quality of life, mCRPC remains incurable.
Conclusions: With the emerging new therapies, this is an unprecedented time in treating mCRPC. A better understanding of their mechanisms of action, the genetic 4SC-202 concentration makeup of each mCRPC, and the development of new prognostic and predictive biomarkers will help determine sequencing or different combination treatments for each individual patient.”
“Study Design. Case report.
Objective. To report on an unusual case of isolated septic discitis, meningitis, pneumocephalus, and solid organ abscesses associated with urosepsis from gas-producing Escherichia coli.
Summary of Background Data. Isolated septic discitis, or disc infection without involvement of adjacent vertebrae, following E. coli urosepsis is an unusual finding in the adult population and to our knowledge has not been reported previously.
Methods. The clinical manifestations and imaging findings of a patient with a history of back pain are described. The significance of the reported case is discussed.
Results.