We are grateful to S. Levy, T. Wakita, J-F. Delagneau, F-L. Cosset, B. Bartosch, R. Bartenschlager, Selleck XAV-939 T. Pietschmann, J. Ball and C.M. Rice for providing us with reagents. We thank the Microscopy-Imaging-Cytometry this website Platform of the Lille Pasteur Campus for access to the instruments and technical advice. This work was supported by the “”Institut Fédératif de Recherche-142″” (IFR142) and by grants from the CNRS and the “”Agence Nationale de Recherches sur le Sida et les

hépatites virales”" ANRS. VRP was supported by a fellowship from the “”Institut Pasteur de Lille/Région Nord Pas-de-Calais”". ML and DD were supported by a fellowship from the ANRS. JC was supported by the Pasteur Institute of Lille and the University of Florida. References 1. Lemon SM, Walker C, Alter MJ, Yi M: Hepatitis C Virus. Fields check details Virology Fifth Edition (Edited by: Knipe DM, Howley PM). Philadelphia: Lippincott Williams & Wilkins 2007, 1:1253–1304. 2. Manns MP, Wedemeyer H, Cornberg M: Treating viral hepatitis C: efficacy, side effects, and complications. Gut 2006,55(9):1350–1359.CrossRefPubMed 3. Bartosch B, Dubuisson J, Cosset F-L: Highly infectious hepatitis C pseudo-viruses containing functional E1E2 envelope protein complexes. J Exp Med 2003,197(5):633–642.CrossRefPubMed 4. Drummer HE, Maerz A, Poumbourios P: Cell surface expression of functional hepatitis C virus E1 and E2 glycoproteins.

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