Science 2005, 309:436–442.selleck chemical PubMedCrossRef 37. Peacock CS, Seeger K, Harris D, Murphy L, Ruiz this website JC, Quail MA, Peters N, Adlem E, Tivey A, Aslett M, Kerhornou A, Ivens A, Fraser A, Rajandream MA, Carver T, Norbertczak H, Chillingworth T, Hance Z, Jagels K, Moule S, Ormond D, Rutter
S, Squares R, Whitehead S, Rabbinowitsch E, Arrowsmith C, White B, Thurston S, Bringaud F, Baldauf SL, Faulconbridge A, Jeffares D, Depledge DP, Oyola SO, Hilley JD, Brito LO, Tosi LR, Barrell B, Cruz AK, Mottram JC, Smith DF, Berriman M: Comparative genomic analysis of three Leishmania species that cause diverse human disease. Nat Genet 2007, 39:839–847.PubMedCrossRef 38. Bringaud
F, Peyruchaud buy VX-770 S, Baltz D, Giroud C, Simpson L, Baltz T: Molecular characterization of the mitochondrial heat shock protein 60 gene from Trypanosoma brucei. Mol Biochem Parasitol 1995, 74:119–123.PubMedCrossRef 39. Bringaud F, Peris M, Zen KH, Simpson L: Characterization of two nuclear-encoded protein components of mitochondrial ribonucleoprotein complexes from Leishmania tarentolae. Mol Biochem Parasitol 1995, 71:65–79.PubMedCrossRef 40. Torri AF, Englund PT: A DNA polymerase b in the mitochondrion of the trypanosomatid Crithidia fasciculata. J Biol Chem 1995,270(8):3495–7.PubMedCrossRef 41. Esponda P, Souto-Padrón T, De Souza W: Fine structure and cytochemistry of the nucleus and the kinetoplast of epimastigotes of Trypanosoma cruzi. J Protozool 1983, 30:105–110.PubMed Authors’ contributions
DPC carried out the experiments and wrote the manuscript. MKS helped to produce the mouse polyclonal antisera. CMP performed the PD184352 (CI-1040) phylogenetic and bioinformatic analysis. TCBSSP provided amastigotes and helped to analyze the results of the imunolabeling assays. WS and SG helped to analyze the results and revised the manuscript. SPF participated in the design and coordination of the study and helped to revise the manuscript. MCMM conceived the study and critically analyzed the paper content. All authors read and approved the final manuscript.”
“Background Bacterial growth requires an appreciable fraction of the acyl chains of the membrane lipids to be in a disordered state[1, 2].