The size of SET ranged from 8 to 120 mm (mean diameter-28,5+15,4 mm). Primary haemostasis was perfomed during endoscopy in 13 (20,3%) patients. As far as the bleeding SET is the absolute indication for their removal 45 (70,3%) patients were operated: open surgery underwent 31 (68,8%), laparoscopic removal – 7 (15,6%), endoscopic removal – 7 (15,6%). Remaining 19 (29,7%) patients were treated conservatively: refuse of patients from operation-9, high operational risk–5, chemotherapy-5. The results of histology and immunohistochemistry: GIST-16; leiomyoma-16; leiomyosarcoma-3; hemangioma-3; lymphoma-2; neurinoma-2;

lipoma-1; mezenhimoma-1; retention cyst-1. Intraoperative complications weren’t observed. Postoperative complications (all after open surgery) were recorded in 4 (6,3%) patients: bleeding from acute ulcer of stomach-1, jugular vein thrombosis-1, acute adhesive intestinal obstruction-1, pulmonary thromboembolism-1. click here Postoperative mortality was 4,4% (2/45), overall mortality – 4,7% (3/64). Conclusion: The EGD+enteroscopy+EUS are valuable methods for diagnostics of bleeding SET and initial haemostasis. Endoscopic and laparoscopic procedures are the method of choice for minimally invasive treatment of patients with bleeding gastrointestinal SET. Key Word(s): 1. subepitelial tumour; 2. bleeding; 3. stomach; 4. enteroscopy; Presenting Author: MAXIM BAGLAENKO Additional Authors: VICTOR STUPIN, VLADIMIR KAHN, SERGEY

SILOUYANOV, VIOLETA BNEYAN, NINA LEVCHUK Corresponding Author: MAXIM BAGLAENKO Affiliations: Moscow Municipal Hospital #15 n. a. O. M. Filatov Objective: Development

of bleeding from stress-induced upper GI ulcers observed selleck inhibitor in 1.5–25% of critically ill patients, the objective is to reduce the risk of bleeding. Methods: In a retrospective study included 517 patients with symptoms of overt upper GI bleeding during the period from 2010 to 2012. 上海皓元医药股份有限公司 In Group 1 enrolled 86 (16.6%) patients with bleeding from stress-induced ulcers during hospital stay. In Group 2 included 431 patients initially hospitalized with signs of bleeding ulcer. Prevention of upper GI ulceration for Group 1 was performed with IV forms of proton pump inhibitors. Results: in Group 1 in 46 (53.5%) patients had ulcers attributed to the high-risk group, which corresponded to FIa, FIIa, FIIb, in Group 2 – in 184 (42.7%) (p = 0.085). HP infection by serological test was positive in 70% in Group 1 and – 73.6% in Group 2 (p = 0,58). NSAIDs registered in 50 (57.9%) patients in Group 1, in Group 2–76 (17.6%) (p = 0.001). The intake of anticoagulants confirmed in 41 (47.4%) patients in Group 1 and in Group 2–29 (6.8%) (p = 0.001). Most of the patients in Group 1–75 (82.7%) had the SAPS II score higher than 30. The rebleeding rate in Group 1 was observed in 13.2% patients in Group 2–7.9% (p = 0.169). In Group 1 8 (7.9%) patients were operated due to unstoppable bleeding, in Group 2–30 (6.9%) (p = 0.92). The mortality in Group 1 was 15.7%, in Group 2–6.25% (p = 0.